annexin vi การใช้

• The annexin VI gene is approximately 60 kbp long and contains 26 exons.
• Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins.
• Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis.
• Annexin VI is thought to be involved in clathrin coated budding events, while annexin II participates in both cholesteryl ester internalization and the biogenesis of multi-vesicular endosomes.
• Exon 21 of annexin VI is alternatively spliced, giving rise to two isoforms that differ by a 6-amino acid insertion at the start of the seventh repeat.